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Overview of CanineSebaceous Adenitis
Sebaceous adenitis, also known as glaucomatous sebaceous adenitis or “SA”, is an uncommon inflammatory skin disease that leads to the destruction of sebaceous glands.
Sebaceous adenitis (SA) is most common in young to middle-aged dogs (1 to 7 years of age). It is genetically inherited and runs in families of dogs. It is thought to be inherited in Poodles, Akitas, and Samoyeds. Other breeds at increased risk include Vizlas, Lhasa apso, German shepherd, and the Bernese mountain dog. It is rare in cats.
The exact cause is not known, but it may be caused by an attack of the immune system against the sebaceous glands responsible for the production of sebum (oil) on the skin. As a consequence, the skin becomes dry and scaly and loses the hair (alopecia). Some dogs may develop skin infection as a consequence of the abnormal skin oil and may become itchy because of the skin infection. Skin infections manifest with odor, papules (red bumps) and excessive shedding. In general, this condition is considered a “cosmetic” problem and does not affect the dogs overall health or lifespan.
The disease starts on top of the head and spreads to the rest of the body. It starts when dogs are one to three years of age and tends to get progressively worse with time.
Screening can be done in dogs belonging to breeds at increased risk for this disease to identify individuals carrying the disease. Biopsies taken from clinically normal skin may already reveal changes suggestive of the condition. Dogs carrying the disease should be excluded from breeding programs due to the genetic nature of this condition.
What to Watch For
These disease may appear differently in different pets. Some pets have a generalized condition while other pets have multiple but focal areas of skin affected. Signs may include:
Diagnosis ofSebaceous Adenitis in Dogs
Other skin diseases may look similar to sebaceous adenitis and must be ruled out by appropriate testing.
The final diagnosis of sebaceous adenitis is made by histopathology, so skin biopsies are normally taken. Since the changes seen with this condition may not be present in all the areas, it is important that several biopsies are taken. Stitches are places in the biopsy sites to ensure fast and proper healing.
Treatment ofSebaceous Adenitis in Dogs
There is no definite cure for this condition. Long term treatments are generally required to control this disease. However, several topical and systemic treatments can be tried to decrease the clinical signs. Control of secondary infections should be treated with antibiotic therapy.
For dogs that do not respond to retinoids, other medications may be tried. Cyclosporines (Atopica®) have been effective in a few refractory cases. This medication is immunosuppressive, which means it suppresses the reaction of the immune system, and therefore has the potential to increase the risk for bacterial infections. Your dog should be closely monitored for adverse effects including vomiting, diarrhea, liver and kidney disease.
In-depth Information on Canine Sebaceous Adenitis
Sebaceous adenitis is an inflammatory disease of the sebaceous (oil) glands leading to the destruction of the glands. Vizlas, Akitas, poodles and Samoyeds are predisposed and the exact pathogenesis has not been established. It seems to be a genetically inherited defect and young dogs are usually affected.
In Poodles, it is believed to be an autosomal recessive mode of inheritance due to the fact that 25 percent of affected dogs may be sub-clinical. Several theories have been formulated to explain this condition:
Related Symptoms or Ailments to Canine SA
Deep skin scrapings should be done in any dog with these clinical signs to rule out demodicosis.
Diagnosis In-depth ofSebaceous Adenitis in Dogs
The early lesions include alopecia (hair loss) with excess scaling and brittle hairs. The top of the head, the dorsal planum of the nose, dorsal neck and dorsal midline are commonly affected areas.
Sebaceous adenitits has a cyclic pattern in some dogs with periods of improvement and worsening. Symptoms are slightly different according to the type of hair coat:
Diagnosis of sebaceous adenitis is made by histopathology, and several biopsies may be needed to make a final diagnosis. Biopsies should be taken from affected and non-affected skin. Subtle early lesions are most useful to document active inflammation.
Secondary bacterial infection and Malassezia dermatitis are commonly present at the time of initial evaluation. Cytology is important to determine the type and severity of the infection. Infections should be cleared before skin biopsies are taken to minimize secondary non-specific changes.
Pathological changes of the tissue vary according to the stage of the disease.
Treatment In-depth ofSebaceous Adenitis in Dogs
Treatments include anti-seborrheic shampoos, emollients, essential fatty acids, antibiotics for the secondary bacterial folliculitis, and retinoids.
Topical therapy:
Systemic Therapy:
Toxicity in animals seems to be less severe than in humans. Adverse effects include: vomiting, diarrhea, erythema, keratoconjunctivitis and stiffness.
Follow-up Care for Dogs withSebaceous Adenitis
This condition is genetic and can be prevented by identifying affected animals and carriers and eliminating these animals from the breeding program.
This is a lifelong condition, thus chronic maintenance therapy (both topical and systemic) is necessary.
FAQs
Sebaceous Adenitis (SA) in Dogs? ›
Sebaceous adenitis destroys the sebaceous glands and sebum is therefore not produced so cannot coat the skin and hair. The lack of moisture retention, along with fibrosis around the hair follicles, contributes to weakened hair shafts, eventually leading to alopecia.
Is sebaceous adenitis painful for dogs? ›Sebaceous adenitis is a painful skin condition in which the immune system attacks the dog's sebaceous glands, causing lesions, sores, hair loss, and often infections.
What is the prognosis for sebaceous adenitis in dogs? ›The prognosis for dogs with sebaceous adenitis is variable and depends on disease severity. It is not curable, but clinically, lesions can improve and the dog can have an excellent quality of life.
What does sebaceous adenitis look like on a dog? ›The signs of sebaceous adenitis in long-haired dogs (e.g., Poodle, Akita, German shepherd, Havanese, and Samoyed) include: Areas of hair loss that are symmetrical from side to side on the body. Dull, brittle haircoat texture. White scales on the skin that do not flake off easily.
What causes sebaceous adenitis? ›The cause of sebaceous adenitis is unknown but the end result is inflammation of the sebaceous or oil gland associated with the hair follicles. Loss of the sebaceous gland leads to dysfunction of normal hair growth, which results in hair loss.
How can I help my dog with sebaceous adenitis? ›Baby oil soaks have historically been used to treat sebaceous adenitis. The oil or a 1:1 dilution with water is massaged into the coat and then left for 1 to 6 h. Thereafter, dogs are bathed using shampoo or dish-washing liquid to remove excess oil. These soaks are recommended every 7 to 30 d (4).
How do I know if my dog has SA? ›If you notice your dog crying, whining, howling, or barking in a very frantic way when you leave the house, then you know you have a dog with SA (separation anxiety). Your dog will do this persistently and there doesn't seem to be a reason or a change to have triggered it except for your absence.
Is sebaceous adenitis an autoimmune disease? ›Sebaceous adenitis is an autoimmune disease whereby the immune system attacks the sebaceous glands in the skin. It is characterized by scaling, alopecia and may or may not be itchy. This autoimmune disease is unique in the sense that it is also heritable.
Is sebaceous adenitis in dogs itchy? ›The condition is generally not itchy unless there is an accompanying bacterial infection in the skin, which probably happens in about 40% of affected dogs. In other words, sebaceous adenitis may or may not be itchy depending on whether there is a concurrent infection.
What age do dogs get sebaceous adenitis? ›Idiopathic sebaceous adenitis has been diagnosed in more than 50 purebred dog breeds and mixes, and dogs typically present between 1 and 5 years of age.
What is the onset of sebaceous adenitis? ›
The disease can develop in a wide age range, with age of onset documented as early as 1 year and as late as 12 years.
How do you test for sebaceous adenitis in dogs? ›The only way to confirm an SA diagnosis is through a skin biopsy performed by a veterinarian. Sebaceous adenitis (SA) is a hereditary skin disease leading to hair loss (alopecia) and changes in your dog's coat texture and color.
Can humans get sebaceous adenitis? ›Sebaceous adenitis is an inflammatory dermatosis most commonly reported in animals. There have been rare reports in humans, mostly on the face and chest, with possible aetiological factors proposed including photodermatosis and Demodex mite.
How often should you bathe a dog with seborrhea? ›Generally, seborrheic dogs will require regular weekly bathing for control of their skin condition. Alternatively, you may be able to control certain effected areas of the skin by using “spot” or “selective” bathing of only the most likely areas of involvement.
How do you treat inflamed sebaceous glands? ›If a small cyst becomes inflamed, your healthcare provider may inject it with a steroid drug to reduce swelling. A healthcare provider may drain a cyst that is large, tender, or inflamed. Larger cysts may need to be removed if they cause hair loss on the scalp, or interfere with clothing.
What are the three common problems related to sebaceous glands? ›Several medical conditions are related with sebaceous gland pathology, such as acne, sebaceous hyperplasia, sebaceous adenoma and sebaceous carcinoma.
Is a sebaceous adenitis painful? ›It generally does not cause pruritus or pain, but pets with this condition are prone to secondary bacterial and/or yeast infections that can cause pruritus, further inflammation, and potential additional hair follicle destruction.
What dog shampoo prevents sebaceous cysts? ›Description. Pet MD Benzoyl Peroxide Shampoo is a is a powerful cleansing and degreasing shampoo for the relief of scaling and itching associated with skin infection, seborrheic disorders, and follicular plugging on dogs and cats.
Can I put Neosporin on my dogs sebaceous cyst? ›You may think that extra-strength Neosporin would be ideal for treating deeper injuries, but avoid its use in your furry pal. Extra-strength Neosporin contains pain-relieving ingredients, which can be detrimental to your pet's health if the ointment is ingested.
Where is the SA node located in a dog? ›In canine and human hearts, the SAN is typically identified as a compact, slightly elongated 3D intramural “banana” shaped structure located at the junction of the superior vena cava and the right atrium, centered around the SAN artery (Fig. 1A) [1,2,4].
What causes sebaceous glands to be overactive in dogs? ›
Hormonal imbalances (e.g., thyroid disease, Cushing's disease) Allergies. Parasites (e.g., fleas, ticks, mange mites) Fungal infections - especially yeast skin infections (Malassezia)
Why does my dog keep getting sebaceous cysts? ›Sebaceous Cysts in Cats or Dogs. A sebaceous cyst can develop when a hair follicle or skin pore gets blocked by dirt, debris, or scar tissue, or as the result of an infection. Our pets, like us, have microscopic oil glands that produce sebum. These glands are called sebaceous glands.
What are the seven disorders of the sebaceous glands? ›- Sebaceous gland.
- Sebum.
- Acne vulgaris.
- Comedone.
- Acne variant.
- Prepubertal acne.
- Neonate acne.
- Infantile acne.
Diseases in which sebaceous glands are primarily implicated include steatocystoma, sebaceous gland hyperplasia, sebaceoma, sebaceous adenoma, nevus sebaceus, and sebaceous carcinoma. Sebaceous glands are secondarily involved in androgenic alopecia, acne vulgaris, and seborrheic dermatitis.
What does inflammation of sebaceous glands lead to? ›Sebaceous gland alteration may play a role in the pathogenesis of common skin diseases including acne vulgaris, atopic dermatitis, psoriasis, rosacea, and seborrheic dermatitis.
Where do dogs itch when they have allergies? ›Symptoms of Allergies in Dogs
Dogs with atopy will usually lick, rub, lick, scratch and bite areas affected like their ears, feet, armpit and groin at their feet, flanks, ears, armpits, or groin.
Causes of Sebaceous Cysts in Dogs
Not only can cysts be unsightly, but they can also emit a foul odor or pus.
Sometimes excessive scratching and chewing from allergies can cause small bumps to form on a dog's skin — and these could indicate a skin infection. Other causes could be anything from acne, ringworm, or mange to various types of cysts and tumors.
Should I take my dog to the vet for a sebaceous cyst? ›You should make an appointment with your vet to address a ruptured or bleeding cyst as soon as you can. This is especially true if your dog is licking or biting the area or you notice signs your dog is in pain.
What dog breeds are prone to sebaceous cysts? ›Sebaceous gland adenoma (a rare, benign lesion) are found in older dogs, typically on the dog's head. Some breeds are predisposed to sebaceous adenoma, including Samoyeds, Siberian huskies, coonhounds, English cocker spaniels, and Alaskan Malamutes.
Can I squeeze my dogs sebaceous cyst? ›
They can be small or grow significantly larger than you'd expect a pimple to. Do not try to pop a cyst on your dog. More often than not a sebaceous cyst will go away on its own either by shrinking away or popping in its own time and releasing a white, pasty substance.
What are the early signs of sebaceous gland carcinoma? ›- Slowly growing, often yellowish lump on the eyelid that feels firm, deep, and painless.
- Thickening of an eyelid, where lid meets lash.
- Yellow or reddish crust on eyelid, where lid meets lash.
- Growth on eyelid that looks like a pimple.
- Growth on eyelid that bleeds.
- Skin redness.
- Tender or sore skin.
- Warm skin in the affected area.
- Grayish-white, cheesy, foul-smelling material that drains from the cyst.
Sebaceous hyperplasia bumps don't usually go away on their own. One exception is newborns. Their bumps usually disappear within a few months.
What does an infected sebaceous cyst look like on a dog? ›Sebaceous cysts appear as a single raised bump that may seem white or slightly blue in color. If it bursts, it will ooze a grayish white, brownish, or cottage-cheese-like discharge. These cysts usually develop on the head, neck, torso, or upper legs. False cysts (those filled with blood) often look dark.
How do you confirm lymphoma in dogs? ›The best way to diagnose lymphoma is to perform a biopsy. A biopsy is a minor surgical procedure to remove a piece of lymph node or other organ affected by cancer. The most common methods for lymph node biopsy are Tru-cut needle biopsy, incisional wedge biopsy, or removal of an entire lymph node (excisional biopsy).
What food is good for dogs with seborrhea? ›Along with their kibble, treat them to servings of chicken, fish, blueberries, kale, and sweet potatoes. Additionally, giving your dog specific vitamins and oils (like olive, flaxseed, and coconut oils) can help to improve their health from the inside out.
Does apple cider vinegar help with seborrhea in dogs? ›Dogs with itchy skin, dandruff, and even fleas may also benefit from apple cider vinegar. One of the best ways to help is to use an apple cider vinegar bath for dogs. The acidity in the vinegar helps balance the pH of the skin, while its antiseptic and antibacterial properties help resolve skin infections naturally.
Is canine seborrhea contagious to other dogs? ›Seborrhea is not contagious to humans or other pets. However, some underlying diseases that cause seborrhea are contagious. For example, fleas can spread from pet to pet, causing seborrhea in both animals if not treated promptly.
What medicine shrinks sebaceous glands? ›Isotretinoin, an oral retinoid, can reduce the amount of sebum the sebaceous glands produce. However, this medication is only suitable for the treatment of severe acne. People should only take isotretinoin as prescribed by a healthcare professional.
Can you squeeze out a sebaceous gland? ›
If you squeeze sebaceous filaments, a waxy, threadlike structure may pop out of your pore. However, you may not squeeze anything out, or you may squeeze out a tiny amount of oil. You should avoid squeezing your sebaceous filaments.
How do you unclog sebaceous glands? ›Over-the-counter medications, creams, and face washes that contain retinol may help clear clogged sebaceous glands. Some people may find that regularly washing the skin with a cleanser containing salicylic acid can help dry-oily skin and prevent clogged glands.
What triggers sebaceous glands? ›Sex hormones traditionally thought of as male, especially testosterone, play a large role in regulating sebaceous gland activity. Sebum production peaks shortly after birth and decreases within the first week of life. During puberty, testosterone floods the body, triggering another spike in sebum production.
What are the 5 disorders of the sebaceous glands? ›Differential diagnosis: Acne comedones, milia, colloid milium, syringoma, trichoepithelioma, and sebaceous gland hyperplasia.
What does a blocked sebaceous gland look like? ›Sebaceous hyperplasia spots are usually 2 to 5 millimeters (. 08 to 0.2 inches) in diameter and may be flesh-colored (for all skin tones) or slightly yellow. If the spots last too long, they may have a similar appearance to basal cell carcinoma.
Does swollen lymph nodes cause pain in dogs? ›Frequently asked questions about swollen lymph nodes in dogs
Swollen lymph nodes are not usually painful. However, if the swollen lymph nodes themselves are infected, they will typically be painful and uncomfortable.
#1: Sebaceous cyst
A sebaceous cyst is essentially a large pimple on your pet's skin. These superficial bumps are clogged oil glands in the skin that are harmless to your pet, although they can become inflamed and sore if they rupture.
Are sebaceous cysts painful? Sebaceous cysts normally don't hurt, but they can become tender, sore and red if they get infected. One sign of infection is redness and swelling around the cyst or foul-smelling drainage seeping out of the cyst. See your healthcare provider if you have such symptoms.
How long does adenitis last? ›Mild, uncomplicated cases of mesenteric lymphadenitis and those caused by a virus usually go away on their own, although full recovery can take four weeks or more.
Are swollen lymph nodes in a dog an emergency? ›It's very important to monitor your dog for signs of recurring illness or swollen lymph nodes. Contact your vet immediately if you notice new swelling in your dog's lymph nodes.
What medication is used for swollen lymph nodes in dogs? ›
Various medications including steroids, anti-inflammatories, antibiotics, anti-parasitics, and even chemotherapy may be recommended depending on the reason for the lymph node enlargement. Surgery or radiation are other treatment possibilities, especially for low-grade, localized lymphomas.
What are the symptoms of the final stages of lymphoma in dogs? ›Lymphoma: End-stage disease can cause dogs to act very lethargic, vomit, have diarrhea, eat less or have no appetite, and lose weight. If the lymph nodes are very large, they can affect breathing because they are blocking the throat. You may notice that your dog has trouble breathing or noisy inhalation (stertor).
How do you calm sebaceous glands? ›- Cleansing regularly. ...
- Limiting alcohol use. ...
- Using salicylic acid products. ...
- Using blotting papers or medicated pads. ...
- Moisturizing regularly. ...
- Making a facial mask. ...
- Using products with green tea. ...
- Making dietary changes.